Reversion of lethality and growth defects in Fatiga oxygen-sensor mutant flies by loss of hypoxia-inducible factor-alpha/Sima.

Reversion of lethality and growth defects in Fatiga oxygen-sensor mutant flies by loss of hypoxia-inducible factor-alpha/Sima.

Hypoxia-Inducible Factor (HIF) prolyl hydroxylase domains (PHDs) have been proposed to act as sensors that have an important role in oxygen homeostasis. In the presence of oxygen, they hydroxylate two specific prolyl residues in HIF-alpha polypeptides, thereby promoting their proteasomal degradation...

Detaylı Bibliyografya
Asıl Yazarlar:	Centanin, L, Ratcliffe, P, Wappner, P
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2005

Benzer Materyaller

Oxygen sensing in Drosophila: multiple isoforms of the prolyl hydroxylase fatiga have different capacity to regulate HIFalpha/Sima.
Yazar:: Julieta M Acevedo, ve diğerleri
Baskı/Yayın Bilgisi: (2010-08-01)

Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha.
Yazar:: Bacon, N, ve diğerleri
Baskı/Yayın Bilgisi: (1998)

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression.
Yazar:: Wood, S, ve diğerleri
Baskı/Yayın Bilgisi: (1998)

miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga.
Yazar:: Ana Laura De Lella Ezcurra, ve diğerleri
Baskı/Yayın Bilgisi: (2016-05-01)

Simas Karaliūnas
Yazar:: Juozas Karaciejus
Baskı/Yayın Bilgisi: (2017-02-01)

The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha.
Yazar:: Willam, C, ve diğerleri
Baskı/Yayın Bilgisi: (2004)

From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway.
Yazar:: Ratcliffe, P
Baskı/Yayın Bilgisi: (2002)

Oxygen sensing and hypoxia-induced responses.
Yazar:: Coleman, M, ve diğerleri
Baskı/Yayın Bilgisi: (2007)

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.
Yazar:: O'Rourke, J, ve diğerleri
Baskı/Yayın Bilgisi: (1999)

Mammalian oxygen sensing and hypoxia inducible factor-1
Yazar:: Wood, S, ve diğerleri
Baskı/Yayın Bilgisi: (1997)

[Šima, Pavel. Hanigovské evanjelium]
Yazar:: Aleš Brandner
Baskı/Yayın Bilgisi: (2013-07-01)

Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer.
Yazar:: Ratcliffe, P
Baskı/Yayın Bilgisi: (2013)

Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage.
Yazar:: Andrew T Moehlman, ve diğerleri
Baskı/Yayın Bilgisi: (2023-07-01)

Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia.
Yazar:: Sowter, H, ve diğerleri
Baskı/Yayın Bilgisi: (2003)

Sima Marković's national and international dialectics
Yazar:: Antolović Mihael T., ve diğerleri
Baskı/Yayın Bilgisi: (2018-01-01)

Fatiga del Occidente
Yazar:: Enrique Puchet C.
Baskı/Yayın Bilgisi: (2016-01-01)

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
Yazar:: Mole, D, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Expression of hypoxia-inducible factors-1alpha and-2alpha in hypoxic and ischemic rat kidneys
Yazar:: Rosenberger, C, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal.
Yazar:: Susan Marino, ve diğerleri
Baskı/Yayın Bilgisi: (2007-06-01)

Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.
Yazar:: Lavista-Llanos, S, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Bibliography of Sima Ćirković, member of the Serbian Academy of Sciences and Arts
Yazar:: Bubalo Đorđe P.
Baskı/Yayın Bilgisi: (2004-01-01)

SIMA: Semilleros de investigación, Mentes Abiertas
Yazar:: Alix Zoraida Bohórquez
Baskı/Yayın Bilgisi: (2004-12-01)

Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys.
Yazar:: Rosenberger, C, ve diğerleri
Baskı/Yayın Bilgisi: (2002)

Síndrome de fatiga crónica
Baskı/Yayın Bilgisi: (2018-03-01)

Síndrome de fatiga Crónica
Yazar:: José Félix Restrepo, ve diğerleri
Baskı/Yayın Bilgisi: (1993-06-01)

Síndrome de fatiga crónica
Yazar:: Mariana Di Rosso, ve diğerleri
Baskı/Yayın Bilgisi: (2008-03-01)

Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression.
Yazar:: Ratcliffe, P, ve diğerleri
Baskı/Yayın Bilgisi: (1998)

Sima M. Ćirković, Srbi među europskim narodima
Yazar:: Dragutin Babić
Baskı/Yayın Bilgisi: (2009-06-01)

The complete mitochondrial genome of Thalamita sima (Decapoda: Portunidae)
Yazar:: Shengping Zhong, ve diğerleri
Baskı/Yayın Bilgisi: (2018-07-01)

Hypoxia, blackwater and fish kills: experimental lethal oxygen thresholds in juvenile predatory lowland river fishes.
Yazar:: Kade Small, ve diğerleri
Baskı/Yayın Bilgisi: (2014-01-01)

Fatiga de los músculos inspiratorios
Yazar:: Peter Macklem
Baskı/Yayın Bilgisi: (2017-07-01)

Discrimination of the Activity of Low-Affinity Wild-Type and High-Affinity Mutant Recombinant BoNT/B by a SIMA Cell-Based Reporter Release Assay
Yazar:: Frank Neuschäfer-Rube, ve diğerleri
Baskı/Yayın Bilgisi: (2022-01-01)

Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit.
Yazar:: Pugh, C, ve diğerleri
Baskı/Yayın Bilgisi: (1997)

Mutantes letais termossensíveis em Aspergillus nidulans Temperature sensitive lethal mutants in Aspergillus nidulans
Yazar:: P. C. de Oliveira, ve diğerleri
Baskı/Yayın Bilgisi: (1975-01-01)

AVOIDANCE OF HYPOXIA IN A CNIDARIAN SYMBIOSIS BY ALGAL PHOTOSYNTHETIC OXYGEN
Yazar:: Rands, M, ve diğerleri
Baskı/Yayın Bilgisi: (1992)

Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
Yazar:: Wiesener, MS, ve diğerleri
Baskı/Yayın Bilgisi: (1998)

Lethal metabolism of Candida albicans respiratory mutants.
Yazar:: D Lucas Kane, ve diğerleri
Baskı/Yayın Bilgisi: (2024-01-01)

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
Yazar:: Masson, N, ve diğerleri
Baskı/Yayın Bilgisi: (2001)

Hypoxia Signalling and Disease
Yazar:: Ratcliffe, P
Baskı/Yayın Bilgisi: (2010)

Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
Yazar:: Gleadle, J, ve diğerleri
Baskı/Yayın Bilgisi: (1995)