Conservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.

BACKGROUND: The immune-related evolution of influenza viruses is exceedingly complex and current vaccines against influenza must be reformulated for each influenza season because of the high degree of antigenic drift among circulating influenza strains. Delay in vaccine production is a serious prob...

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Autors principals: Tan, P, Heiny, A, Miotto, O, Salmon, J, Marques, E, Lemonnier, F, August, J
Format: Journal article
Idioma:English
Publicat: 2010