Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.
TLRs are key innate immune receptors that recognize conserved features of biological molecules that are found in microbes. In particular, TLR2 has been reported to be activated by different kinds of microbial ligands. To advance our understanding of the interaction of TLR2 with its ligands, the reco...
Main Authors: | Jiménez-Dalmaroni, M, Radcliffe, C, Harvey, D, Wormald, M, Verdino, P, Ainge, G, Larsen, D, Painter, G, Ulevitch, R, Beutler, B, Rudd, P, Dwek, R, Wilson, I |
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Format: | Journal article |
Language: | English |
Published: |
SAGE Publications
2015
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