Fool's gold: Why imperfect reference tests are undermining the evaluation of novel diagnostics: a reevaluation of 5 diagnostic tests for leptospirosis.

BACKGROUND: We observed that some patients with clinical leptospirosis supported by positive results of rapid tests were negative for leptospirosis on the basis of our diagnostic gold standard, which involves isolation of Leptospira species from blood culture and/or a positive result of a microscopi...

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Detalhes bibliográficos
Principais autores: Limmathurotsakul, D, Turner, E, Wuthiekanun, V, Thaipadungpanit, J, Suputtamongkol, Y, Chierakul, W, Smythe, L, Day, N, Cooper, B, Peacock, S
Formato: Journal article
Idioma:English
Publicado em: 2012