Meta-analysis of expression of l(3)mbt tumor-associated germline genes supports the model that a soma-to-germline transition is a hallmark of human cancers.

Evidence is starting to emerge indicating that tumorigenesis in metazoans involves a soma-to-germline transition, which may contribute to the acquisition of neoplastic characteristics. Here, we have meta-analyzed gene expression profiles of the human orthologs of Drosophila melanogaster germline gen...

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Detalhes bibliográficos
Principais autores: Feichtinger, J, Larcombe, L, McFarlane, R
Formato: Journal article
Idioma:English
Publicado em: Wiley-Liss Inc. 2014