Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib.

The proteasome inhibitor bortezomib has shown impressive clinical activity alone and in combination with conventional and other novel agents for the treatment of multiple myeloma (MM). Although bortezomib is known to be a selective proteasome inhibitor, the downstream mechanisms of cytotoxicity and...

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Main Authors: Shringarpure, R, Catley, L, Bhole, D, Burger, R, Podar, K, Tai, Y, Kessler, B, Galardy, P, Ploegh, H, Tassone, P, Hideshima, T, Mitsiades, C, Munshi, N, Chauhan, D, Anderson, K
格式: Journal article
语言:English
出版: 2006