Age-dependent and -independent behavioral deficits in Tg2576 mice.

The Tg2576 mouse model of excessive cerebral beta-amyloid deposition is now more than a decade old, yet consensus as to its exact characteristics and utility as a model of Alzheimer's disease is still lacking. Four different cohorts of control and Tg2576 mice, aged approximately 3, 9, 13 and 21...

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Bibliographic Details
Main Authors: Deacon, R, Cholerton, L, Talbot, K, Nair-Roberts, R, Sanderson, D, Romberg, C, Koros, E, Bornemann, K, Rawlins, J
Format: Journal article
Language:English
Published: 2008