Age-dependent and -independent behavioral deficits in Tg2576 mice.

Age-dependent and -independent behavioral deficits in Tg2576 mice.

The Tg2576 mouse model of excessive cerebral beta-amyloid deposition is now more than a decade old, yet consensus as to its exact characteristics and utility as a model of Alzheimer's disease is still lacking. Four different cohorts of control and Tg2576 mice, aged approximately 3, 9, 13 and 21...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Deacon, R, Cholerton, L, Talbot, K, Nair-Roberts, R, Sanderson, D, Romberg, C, Koros, E, Bornemann, K, Rawlins, J
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2008

Ижил төстэй зүйлс

Aged Tg2576 mice are impaired on social memory and open field habituation tests.
-н: Deacon, R, зэрэг
Хэвлэсэн: (2009)

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice
-н: Rogers Kathryn, зэрэг
Хэвлэсэн: (2012-12-01)

Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
-н: A. Parachikova, зэрэг
Хэвлэсэн: (2008-04-01)

Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels.
-н: Anna M Lilja, зэрэг
Хэвлэсэн: (2013-01-01)

Cholinergic denervation exacerbates amyloid pathology and induces hippocampal atrophy in Tg2576 mice
-н: Francisco J. Gil-Bea, зэрэг
Хэвлэсэн: (2012-12-01)

Correction: Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels
Хэвлэсэн: (2013-01-01)

Correction: Age-Dependent Neuroplasticity Mechanisms in Alzheimer Tg2576 Mice Following Modulation of Brain Amyloid-β Levels.
-н: Anna M. Lilja, зэрэг
Хэвлэсэн: (2013-01-01)

Significant structural but not physiological changes in cortical neurons of 12-month-old Tg2576 mice
-н: Anne B. Rocher, зэрэг
Хэвлэсэн: (2008-11-01)

Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer’s-like clinical phenotype
-н: Luca Lorenzini, зэрэг
Хэвлэсэн: (2024-05-01)

Oat Extract Avenanthramide-C Reverses Hippocampal Long-Term Potentiation Decline in Tg2576 Mice
-н: Yu-Young Lee, зэрэг
Хэвлэсэн: (2021-10-01)

ASSOCIATION OF BEHAVIOURAL AND COGNITIVE TRAITS WITH GASTROINTESTINAL REDOX HOMEOSTASIS IN SYMPTOMATIC MIDDLE-AGED TG2576 MICE
-н: Ana Babić Perhoč, зэрэг
Хэвлэсэн: (2023-10-01)

Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
-н: T.A Lanz, зэрэг
Хэвлэсэн: (2003-08-01)

Docosahexaenoic Acid Ameliorates Contextual Fear Memory Deficits in the Tg2576 Alzheimer’s Disease Mouse Model: Cellular and Molecular Correlates
-н: Sara Badesso, зэрэг
Хэвлэсэн: (2022-12-01)

Resilience to structural and molecular changes in excitatory synapses in the hippocampus contributes to cognitive function recovery in Tg2576 mice
-н: Carolina Aguado, зэрэг
Хэвлэсэн: (2024-01-01)

S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model.
-н: Tae-Young Ha, зэрэг
Хэвлэсэн: (2010-01-01)

Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Aβ pathology
-н: Antonella Borreca, зэрэг
Хэвлэсэн: (2020-06-01)

Tg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegeneration.
-н: Shannon Ray, зэрэг
Хэвлэсэн: (2011-04-01)

Insulin resistance contributes to aberrant stress responses in the Tg2576 mouse model of Alzheimer's disease
-н: Ward A. Pedersen, зэрэг
Хэвлэсэн: (2004-12-01)

Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice.
-н: Hao Cui, зэрэг
Хэвлэсэн: (2011-01-01)

Paraoxonase-1 and -3 Protein Expression in the Brain of the Tg2576 Mouse Model of Alzheimer’s Disease
-н: Jose Gregorio Salazar, зэрэг
Хэвлэсэн: (2021-02-01)

In vivo turnover of tau and APP metabolites in the brains of wild-type and Tg2576 mice: greater stability of sAPP in the beta-amyloid depositing mice.
-н: Jose Morales-Corraliza, зэрэг
Хэвлэсэн: (2009-09-01)

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.
-н: Hee Jin Kim, зэрэг
Хэвлэсэн: (2014-01-01)

Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice
-н: Livia La Barbera, зэрэг
Хэвлэсэн: (2022-11-01)

Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
-н: Cribbs David H, зэрэг
Хэвлэсэн: (2008-04-01)

Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice
-н: Martín-Moreno Ana María, зэрэг
Хэвлэсэн: (2012-01-01)

VEEV TC-83 Triggers Dysregulation of the Tryptophan–Kynurenine Pathway in the Central Nervous System That Correlates with Cognitive Impairment in Tg2576 Mice
-н: Chanida Fongsaran, зэрэг
Хэвлэсэн: (2024-05-01)

Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease.
-н: Alice Krezymon, зэрэг
Хэвлэсэн: (2013-01-01)

Environmental enrichment does not influence hypersynchronous network activity in the Tg2576 mouse model of Alzheimer’s disease
-н: Charlotte eBezzina, зэрэг
Хэвлэсэн: (2015-09-01)

Exercise Training Results in Lower Amyloid Plaque Load and Greater Cognitive Function in an Intensity Dependent Manner in the Tg2576 Mouse Model of Alzheimer’s Disease
-н: Riya Thomas, зэрэг
Хэвлэсэн: (2020-02-01)

Brain and Brown Adipose Tissue Metabolism in Transgenic Tg2576 Mice Models of Alzheimer Disease Assessed Using F-FDG PET Imaging
-н: Robert A. Coleman PhD, зэрэг
Хэвлэсэн: (2017-04-01)

Evidence for a protective effect of the loss of α4-containing nicotinic acetylcholine receptors on Aβ-related neuropathology in Tg2576 mice
-н: Antonietta Vilella, зэрэг
Хэвлэсэн: (2023-04-01)

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease
-н: Mercedes Lachen-Montes, зэрэг
Хэвлэсэн: (2019-06-01)

Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes
-н: Vito Antonio Baldassarro, зэрэг
Хэвлэсэн: (2017-05-01)

Mannan-Abeta<sub>28 </sub>conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice
-н: Karapetyan Adrine, зэрэг
Хэвлэсэн: (2008-09-01)

Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease
-н: Alberto Cordella, зэрэг
Хэвлэсэн: (2018-08-01)

Constipation in Tg2576 mice model for Alzheimer's disease associated with dysregulation of mechanism involving the mAChR signaling pathway and ER stress response.
-н: Ji Eun Kim, зэрэг
Хэвлэсэн: (2019-01-01)

Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy
-н: Chakrabarty Paramita, зэрэг
Хэвлэсэн: (2006-07-01)

Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice
-н: Hyeon Joo Ham, зэрэг
Хэвлэсэн: (2019-10-01)

Immunohistochemical Demonstration of the pGlu79 α-Synuclein Fragment in Alzheimer’s Disease and Its Tg2576 Mouse Model
-н: Alexandra Bluhm, зэрэг
Хэвлэсэн: (2022-07-01)

Asparagus cochinchinensis stimulates release of nerve growth factor and abrogates oxidative stress in the Tg2576 model for Alzheimer’s disease
-н: Hyun Ah Lee, зэрэг
Хэвлэсэн: (2018-04-01)