Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses.
Gv1 is a genetic locus that coordinately regulates the expression of multiple murine leukemia virus-related endogenous proviral sequences. A quantitative nuclease protection assay for typing Gv1 inheritance has been developed. Use of this assay demonstrates that Gv1 controls transcription of polytro...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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1999
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| _version_ | 1797099885886963712 |
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| author | Oliver, P Stoye, J |
| author_facet | Oliver, P Stoye, J |
| author_sort | Oliver, P |
| collection | OXFORD |
| description | Gv1 is a genetic locus that coordinately regulates the expression of multiple murine leukemia virus-related endogenous proviral sequences. A quantitative nuclease protection assay for typing Gv1 inheritance has been developed. Use of this assay demonstrates that Gv1 controls transcription of polytropic but not of modified polytropic endogenous proviruses. A combination of genetic techniques were used to map Gv1; these analyses demonstrate that Gv1 lies approximately 37 centimorgans from the centromeric end of mouse chromosome 13. |
| first_indexed | 2024-03-07T05:29:58Z |
| format | Journal article |
| id | oxford-uuid:e1ea1842-0c39-4633-9c23-926944182a74 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:29:58Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:e1ea1842-0c39-4633-9c23-926944182a742022-03-27T09:57:29ZGenetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e1ea1842-0c39-4633-9c23-926944182a74EnglishSymplectic Elements at Oxford1999Oliver, PStoye, JGv1 is a genetic locus that coordinately regulates the expression of multiple murine leukemia virus-related endogenous proviral sequences. A quantitative nuclease protection assay for typing Gv1 inheritance has been developed. Use of this assay demonstrates that Gv1 controls transcription of polytropic but not of modified polytropic endogenous proviruses. A combination of genetic techniques were used to map Gv1; these analyses demonstrate that Gv1 lies approximately 37 centimorgans from the centromeric end of mouse chromosome 13. |
| spellingShingle | Oliver, P Stoye, J Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title | Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title_full | Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title_fullStr | Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title_full_unstemmed | Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title_short | Genetic analysis of Gv1, a gene controlling transcription of endogenous murine polytropic proviruses. |
| title_sort | genetic analysis of gv1 a gene controlling transcription of endogenous murine polytropic proviruses |
| work_keys_str_mv | AT oliverp geneticanalysisofgv1agenecontrollingtranscriptionofendogenousmurinepolytropicproviruses AT stoyej geneticanalysisofgv1agenecontrollingtranscriptionofendogenousmurinepolytropicproviruses |