HLA*IMP--an integrated framework for imputing classical HLA alleles from SNP genotypes.

HLA*IMP--an integrated framework for imputing classical HLA alleles from SNP genotypes.

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MOTIVATION: Genetic variation at classical HLA alleles influences many phenotypes, including susceptibility to autoimmune disease, resistance to pathogens and the risk of adverse drug reactions. However, classical HLA typing methods are often prohibitively expensive for large-scale studies. We previ...

Bibliografski detalji
Glavni autori:	Dilthey, A, Moutsianas, L, Leslie, S, McVean, G
Format:	Journal article
Jezik:	English
Izdano:	2011

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