Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance.
CD40L antibodies have proven to be powerful immunosuppressive agents in nonhuman primates but unfortunately perturb blood coagulation. Neither the therapeutic nor the prothrombotic mechanism of anti-CD40L is defined sufficiently to determine whether these effects can be uncoupled. Recent evidence su...
| Główni autorzy: | , , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
2008
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