Evidence for a novel neuronal mechanism driving Alzheimer's disease, upstream of amyloid

Evidence for a novel neuronal mechanism driving Alzheimer's disease, upstream of amyloid

This perspective offers an alternative to the amyloid hypothesis in the etiology of Alzheimer's disease (AD). We review evidence for a novel signaling mechanism based on a little‐known peptide, T14. T14 could drive neurodegeneration as an aberrantly activated process of plasticity selective to...

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Bibliographic Details
Main Authors:	Garcia Ratés, S, García‐Ayllón, M, Falgàs, N, Brangman, SA, Esiri, MM, Coen, CW, Greenfield, SA
Format:	Journal article
Language:	English
Published:	Wiley Open Access 2024

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