DNA repair factor APLF is a histone chaperone.

Poly(ADP-ribosyl)ation plays a major role in DNA repair, where it regulates chromatin relaxation as one of the critical events in the repair process. However, the molecular mechanism by which poly(ADP-ribose) modulates chromatin remains poorly understood. Here we identify the poly(ADP-ribose)-regula...

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Hlavní autoři: Mehrotra, P, Ahel, D, Ryan, D, Weston, R, Wiechens, N, Kraehenbuehl, R, Owen-Hughes, T, Ahel, I
Médium: Journal article
Jazyk:English
Vydáno: 2011