FOXP1: a potential therapeutic target in cancer.

FOXP1: a potential therapeutic target in cancer.

Forkhead Box P1 (FOXP1) is a member of the FOX family of transcription factors which have a broad range of functions. Foxp1 is widely expressed and has been shown to have a role in cardiac, lung and lymphocyte development. FOXP1 is targeted by recurrent chromosome translocations and its overexpressi...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Koon, H, Ippolito, G, Banham, A, Tucker, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2007

Παρόμοια τεκμήρια

Therapeutic targeting of FOXP3-positive regulatory T cells using a FOXP3 peptide vaccine WO2008081581.
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circFOXP1: a potential diagnostic and therapeutic target in human diseases
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Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma
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The significance of FOXP1 in diffuse large B-cell lymphoma
ανά: Gascoyne, D, κ.ά.
Έκδοση: (2016)

The FOXP3 transcription factor as a regulatory T-cell marker
ανά: Banham, A
Έκδοση: (2008)

FOXP3+ regulatory T cells as biomarkers in human malignancies.
ανά: Bignone, P, κ.ά.
Έκδοση: (2008)

Characterization of human FOXP1 isoform 2, using monoclonal antibody 4E3-G11, and intron retention as a tissue-specific mechanism generating a novel FOXP1 isoform.
ανά: Brown, P, κ.ά.
Έκδοση: (2008)

Is FOXP3 expressed in cutaneous T-cell lymphomas?
ανά: Banham, A, κ.ά.
Έκδοση: (2008)

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells.
ανά: Brown, P, κ.ά.
Έκδοση: (2016)

Monoclonal antibodies raised to the human FOXP3 protein can be used effectively for detecting Foxp3(+) T cells in other mammalian species.
ανά: Banham, A, κ.ά.
Έκδοση: (2009)

Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells.
ανά: Banham, A
Έκδοση: (2006)

FOXP3+ regulatory T cells: Current controversies and future perspectives.
ανά: Banham, A, κ.ά.
Έκδοση: (2006)

The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer.
ανά: Giatromanolaki, A, κ.ά.
Έκδοση: (2008)

MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas.
ανά: Borovecki, A, κ.ά.
Έκδοση: (2007)

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells
ανά: Philip J. Brown, κ.ά.
Έκδοση: (2016-07-01)

The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphoma.
ανά: Brown, P, κ.ά.
Έκδοση: (2005)

Immunologic targeting of FOXP3 in inflammatory breast cancer cells.
ανά: Smita Nair, κ.ά.
Έκδοση: (2013-01-01)

Expression of FOXP2 is up-regulated in lymphoid malignancies
ανά: Campbell, A, κ.ά.
Έκδοση: (2009)

Expression of the forkhead box transcription factor FOXP1 is associated with oestrogen receptor alpha, oestrogen receptor beta and improved survival in familial breast cancers.
ανά: Rayoo, M, κ.ά.
Έκδοση: (2009)

Defense of the clone: antibody 259D effectively labels human FOXP3 in a variety of applications.
ανά: Fox, B, κ.ά.
Έκδοση: (2008)

FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma
ανά: Giatromanolaki, A, κ.ά.
Έκδοση: (2019)

Therapeutic efficacy of ECs Foxp1 targeting Hif1α-Hk2 glycolysis signal to restrict angiogenesis
ανά: Jingjiang Pi, κ.ά.
Έκδοση: (2024-09-01)

FOXP3 expression in B and T cell lymphomas.
ανά: Roncador, G, κ.ά.
Έκδοση: (2005)

Potentially oncogenic B-cell activation-induced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL.
ανά: Brown, P, κ.ά.
Έκδοση: (2008)

FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control.
ανά: Goatly, A, κ.ά.
Έκδοση: (2008)

FOXP1 abnormalities in lymphoma: Translocation breakpoint mapping reveals insights into deregulated transcriptional control
ανά: Goatly, A, κ.ά.
Έκδοση: (2008)

FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions
ανά: Payal Grover, κ.ά.
Έκδοση: (2021-02-01)

Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas.
ανά: Bates, G, κ.ά.
Έκδοση: (2008)

Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
ανά: Banham, A, κ.ά.
Έκδοση: (2007)

Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations.
ανά: Fuchizawa, T, κ.ά.
Έκδοση: (2007)

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease.
ανά: Saruta, M, κ.ά.
Έκδοση: (2007)

Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas.
ανά: Nyman, H, κ.ά.
Έκδοση: (2009)

BCL-2 but not FOXP1, is an adverse risk factor in immunochemotherapy treated non-germinal center diffuse large B-cell lymphomas
ανά: Nyman, H, κ.ά.
Έκδοση: (2008)

Immunomodulation of FOXP3+ regulatory T cells by the aromatase inhibitor letrozole in breast cancer patients.
ανά: Generali, D, κ.ά.
Έκδοση: (2009)

Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome.
ανά: Barrans, S, κ.ά.
Έκδοση: (2004)

Exploring the expression of the androgen receptor (AR) in prostate cancer: Its relationship to the vascular endothelial growth factor (VEGF), hypoxia inducible factors (HIF) 1 and 2 and the novel forkhead transcription factor, FOXP1
ανά: Boddy, J, κ.ά.
Έκδοση: (2005)

Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.
ανά: Banham, A, κ.ά.
Έκδοση: (2005)

Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis.
ανά: Yu, Q, κ.ά.
Έκδοση: (2007)

Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1alpha expression.
ανά: Giatromanolaki, A, κ.ά.
Έκδοση: (2006)

Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas.
ανά: Fox, S, κ.ά.
Έκδοση: (2004)