FOXP1: a potential therapeutic target in cancer.

FOXP1: a potential therapeutic target in cancer.

Forkhead Box P1 (FOXP1) is a member of the FOX family of transcription factors which have a broad range of functions. Foxp1 is widely expressed and has been shown to have a role in cardiac, lung and lymphocyte development. FOXP1 is targeted by recurrent chromosome translocations and its overexpressi...

Повний опис

Бібліографічні деталі
Автори:	Koon, H, Ippolito, G, Banham, A, Tucker, P
Формат:	Journal article
Мова:	English
Опубліковано:	2007

Схожі ресурси

Therapeutic targeting of FOXP3-positive regulatory T cells using a FOXP3 peptide vaccine WO2008081581.
за авторством: Banham, A, та інші
Опубліковано: (2009)

circFOXP1: a potential diagnostic and therapeutic target in human diseases
за авторством: Qiang Yi, та інші
Опубліковано: (2024-11-01)

Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma
за авторством: Camilleri, E, та інші
Опубліковано: (2012)

The significance of FOXP1 in diffuse large B-cell lymphoma
за авторством: Gascoyne, D, та інші
Опубліковано: (2016)

The FOXP3 transcription factor as a regulatory T-cell marker
за авторством: Banham, A
Опубліковано: (2008)

FOXP3+ regulatory T cells as biomarkers in human malignancies.
за авторством: Bignone, P, та інші
Опубліковано: (2008)

Characterization of human FOXP1 isoform 2, using monoclonal antibody 4E3-G11, and intron retention as a tissue-specific mechanism generating a novel FOXP1 isoform.
за авторством: Brown, P, та інші
Опубліковано: (2008)

Is FOXP3 expressed in cutaneous T-cell lymphomas?
за авторством: Banham, A, та інші
Опубліковано: (2008)

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells.
за авторством: Brown, P, та інші
Опубліковано: (2016)

Monoclonal antibodies raised to the human FOXP3 protein can be used effectively for detecting Foxp3(+) T cells in other mammalian species.
за авторством: Banham, A, та інші
Опубліковано: (2009)

Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T cells.
за авторством: Banham, A
Опубліковано: (2006)

FOXP3+ regulatory T cells: Current controversies and future perspectives.
за авторством: Banham, A, та інші
Опубліковано: (2006)

The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer.
за авторством: Giatromanolaki, A, та інші
Опубліковано: (2008)

MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas.
за авторством: Borovecki, A, та інші
Опубліковано: (2007)

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells
за авторством: Philip J. Brown, та інші
Опубліковано: (2016-07-01)

The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphoma.
за авторством: Brown, P, та інші
Опубліковано: (2005)

Immunologic targeting of FOXP3 in inflammatory breast cancer cells.
за авторством: Smita Nair, та інші
Опубліковано: (2013-01-01)

Expression of FOXP2 is up-regulated in lymphoid malignancies
за авторством: Campbell, A, та інші
Опубліковано: (2009)

Expression of the forkhead box transcription factor FOXP1 is associated with oestrogen receptor alpha, oestrogen receptor beta and improved survival in familial breast cancers.
за авторством: Rayoo, M, та інші
Опубліковано: (2009)

Defense of the clone: antibody 259D effectively labels human FOXP3 in a variety of applications.
за авторством: Fox, B, та інші
Опубліковано: (2008)

FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma
за авторством: Giatromanolaki, A, та інші
Опубліковано: (2019)

Therapeutic efficacy of ECs Foxp1 targeting Hif1α-Hk2 glycolysis signal to restrict angiogenesis
за авторством: Jingjiang Pi, та інші
Опубліковано: (2024-09-01)

FOXP3 expression in B and T cell lymphomas.
за авторством: Roncador, G, та інші
Опубліковано: (2005)

Potentially oncogenic B-cell activation-induced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL.
за авторством: Brown, P, та інші
Опубліковано: (2008)

FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control.
за авторством: Goatly, A, та інші
Опубліковано: (2008)

FOXP1 abnormalities in lymphoma: Translocation breakpoint mapping reveals insights into deregulated transcriptional control
за авторством: Goatly, A, та інші
Опубліковано: (2008)

FOXP3 and Tip60 Structural Interactions Relevant to IPEX Development Lead to Potential Therapeutics to Increase FOXP3 Dependent Suppressor T Cell Functions
за авторством: Payal Grover, та інші
Опубліковано: (2021-02-01)

Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas.
за авторством: Bates, G, та інші
Опубліковано: (2008)

Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
за авторством: Banham, A, та інші
Опубліковано: (2007)

Developmental changes of FOXP3-expressing CD4+CD25+ regulatory T cells and their impairment in patients with FOXP3 gene mutations.
за авторством: Fuchizawa, T, та інші
Опубліковано: (2007)

Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease.
за авторством: Saruta, M, та інші
Опубліковано: (2007)

Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas.
за авторством: Nyman, H, та інші
Опубліковано: (2009)

BCL-2 but not FOXP1, is an adverse risk factor in immunochemotherapy treated non-germinal center diffuse large B-cell lymphomas
за авторством: Nyman, H, та інші
Опубліковано: (2008)

Immunomodulation of FOXP3+ regulatory T cells by the aromatase inhibitor letrozole in breast cancer patients.
за авторством: Generali, D, та інші
Опубліковано: (2009)

Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome.
за авторством: Barrans, S, та інші
Опубліковано: (2004)

Exploring the expression of the androgen receptor (AR) in prostate cancer: Its relationship to the vascular endothelial growth factor (VEGF), hypoxia inducible factors (HIF) 1 and 2 and the novel forkhead transcription factor, FOXP1
за авторством: Boddy, J, та інші
Опубліковано: (2005)

Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.
за авторством: Banham, A, та інші
Опубліковано: (2005)

Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis.
за авторством: Yu, Q, та інші
Опубліковано: (2007)

Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1alpha expression.
за авторством: Giatromanolaki, A, та інші
Опубліковано: (2006)

Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas.
за авторством: Fox, S, та інші
Опубліковано: (2004)