Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.

Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.

OBJECTIVE: A compelling genetic association with osteoarthritis (OA) of 2 functional alleles in the aspartic acid (D) repeat of the asporin gene was recently reported in a Japanese population. Allele D13 of the repeat encoded OA protection, whereas allele D14 encoded OA susceptibility. The 2 allele...

书目详细资料
Main Authors:	Mustafa, Z, Dowling, B, Chapman, K, Sinsheimer, J, Carr, A, Loughlin, J
格式:	Journal article
语言:	English
出版:	2005

相似书籍

The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population.
由: Loughlin, J, et al.
出版: (2006)

Association between aspartic acid repeat polymorphism of the asporin gene and risk of knee osteoarthritis: A systematic review and meta-analysis
由: Mohammad Reza Sobhan, et al.
出版: (2017-10-01)

An updated meta-analysis of the asporin gene D-repeat in knee osteoarthritis: effects of gender and ethnicity
由: Ruoxi Liu, et al.
出版: (2017-10-01)

Serum asporin levels in maintenance hemodialysis patients without osteoarthritis
由: Ali Doğan Dursun, et al.
出版: (2023-03-01)

Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis
由: Mari Taipale, et al.
出版: (2017-12-01)

Presence of a primary hip osteoarthritis susceptibility locus on chromosome 6: comment on the article by Meenagh et al.
由: Chapman, K, et al.
出版: (2006)

Asporin Gene Expression in Mouse Alveogenesis
由: Lakkana Wongkhat, et al.
出版: (2017-04-01)

Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus.
由: Snelling, S, et al.
出版: (2007)

Genetic association analysis of RHOB and TXNDC3 in osteoarthritis.
由: Loughlin, J, et al.
出版: (2007)

Finer linkage mapping of two regions harbouring suggestive susceptibility loci for osteoarthritis.
由: Chapman, K, et al.
出版: (2001)

Finer linkage mapping of primary hip osteoarthritis susceptibility on chromosome 11q in a cohort of affected female sibling pairs.
由: Chapman, K, et al.
出版: (2002)

Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis.
由: Chitnavis, J, et al.
出版: (1997)

Linkage analysis of candidate genes as susceptibility loci for osteoarthritis-suggestive linkage of COL9A1 to female hip osteoarthritis.
由: Mustafa, Z, et al.
出版: (2000)

Glycoprotein asporin as a novel player in tumour microenvironment and cancer progression
由: Dana Simkova, et al.
出版: (2016-12-01)

Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosis
由: Dipjit Basak, et al.
出版: (2021-01-01)

Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosis.
由: Dipjit Basak, et al.
出版: (2021-01-01)

Association analysis of the vitamin D receptor gene, the type I collagen gene COL1A1, and the estrogen receptor gene in idiopathic osteoarthritis.
由: Loughlin, J, et al.
出版: (2000)

Linkage analysis of chromosome 2q in osteoarthritis.
由: Loughlin, J, et al.
出版: (2000)

Osteoarthritis-susceptibility locus on chromosome 11q, detected by linkage.
由: Chapman, K, et al.
出版: (1999)

Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13.
由: Southam, L, et al.
出版: (2004)

Asporin-deficient mice have tougher skin and altered skin glycosaminoglycan content and structure.
由: Marco Maccarana, et al.
出版: (2017-01-01)

Genetic influences in the aetiology of anteromedial osteoarthritis of the knee.
由: McDonnell, S, et al.
出版: (2007)

First time and repeat caucasian visitors to Singapore.
由: Chong, Yoke Ting., et al.
出版: (2008)

PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
由: Burr, M, et al.
出版: (2010)

A female-specific susceptibility gene for idiopathic osteoarthritis is located on chromosome 11q
由: Loughlin, J, et al.
出版: (1999)

Stratification analysis of an osteoarthritis genome screen-suggestive linkage to chromosomes 4, 6, and 16.
由: Loughlin, J, et al.
出版: (1999)

Coronal and axial alignment relationship in Caucasian patients with osteoarthritis of the knee
由: Vicente J. León-Muñoz, et al.
出版: (2021-04-01)

Comparative Evaluation of Periodontal Ligament-associated Protein-1/Asporin Levels in Periodontal Tissue in Health and Disease
由: Madhu Priya Manohar, et al.
出版: (2024-07-01)

Asporin Interacts With HER2 to Promote Thyroid Cancer Metastasis via the MAPK/EMT Signaling Pathway
由: Shaohua Zhan, et al.
出版: (2022-05-01)

End-stage coxarthrosis and gonarthrosis. Aetiology, clinical patterns and radiological features of idiopathic osteoarthritis.
由: Chitnavis, J, et al.
出版: (2000)

Phenotype-Genotype analysis of caucasian patients with high risk of osteoarthritis
由: Yanfei Wang, et al.
出版: (2022-08-01)

Recent advances in the genetic investigation of osteoarthritis.
由: Peach, C, et al.
出版: (2005)

Population Pharmacokinetics of Valproic Acid in Pediatric and Adult Caucasian Patients
由: Paulo Teixeira-da-Silva, et al.
出版: (2022-04-01)

Lack of association of the vitamin D receptor gene with Graves' disease in UK Caucasians.
由: Collins, J, et al.
出版: (2004)

Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro
由: Anisha Polley, et al.
出版: (2020-01-01)

Myocardial fibrosis and calcification are attenuated by microRNA–129-5p targeting Asporin and Sox9 in cardiac fibroblasts
由: Lejla Medzikovic, et al.
出版: (2023-05-01)

Genetic association analysis of the IGFBP7, ADAMTS3, and IL8 genes as the potential osteoarthritis susceptibility that maps to chromosome 4q.
由: Kawahara, C, et al.
出版: (2005)

Genetic background increases the risk of hip osteoarthritis.
由: Spencer, J, et al.
出版: (2005)

Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.
由: Pamela Maris, et al.
出版: (2015-09-01)

Butyrylcholinesterase K variant is associated with type 2 diabetes in UK Caucasians
由: Hashim, Y, et al.
出版: (2000)