Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.

Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.

OBJECTIVE: A compelling genetic association with osteoarthritis (OA) of 2 functional alleles in the aspartic acid (D) repeat of the asporin gene was recently reported in a Japanese population. Allele D13 of the repeat encoded OA protection, whereas allele D14 encoded OA susceptibility. The 2 allele...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Mustafa, Z, Dowling, B, Chapman, K, Sinsheimer, J, Carr, A, Loughlin, J
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2005

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ανά: Chapman, K, κ.ά.
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ανά: Chitnavis, J, κ.ά.
Έκδοση: (1997)

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ανά: Mustafa, Z, κ.ά.
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ανά: Loughlin, J, κ.ά.
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ανά: Chapman, K, κ.ά.
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ανά: Southam, L, κ.ά.
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First time and repeat caucasian visitors to Singapore.
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ανά: Burr, M, κ.ά.
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ανά: Loughlin, J, κ.ά.
Έκδοση: (1999)

Stratification analysis of an osteoarthritis genome screen-suggestive linkage to chromosomes 4, 6, and 16.
ανά: Loughlin, J, κ.ά.
Έκδοση: (1999)

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ανά: Vicente J. León-Muñoz, κ.ά.
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End-stage coxarthrosis and gonarthrosis. Aetiology, clinical patterns and radiological features of idiopathic osteoarthritis.
ανά: Chitnavis, J, κ.ά.
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ανά: Hashim, Y, κ.ά.
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