Investigating the aspartic acid (D) repeat of asporin as a risk factor for osteoarthritis in a UK Caucasian population.

OBJECTIVE: A compelling genetic association with osteoarthritis (OA) of 2 functional alleles in the aspartic acid (D) repeat of the asporin gene was recently reported in a Japanese population. Allele D13 of the repeat encoded OA protection, whereas allele D14 encoded OA susceptibility. The 2 allele...

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Hlavní autoři: Mustafa, Z, Dowling, B, Chapman, K, Sinsheimer, J, Carr, A, Loughlin, J
Médium: Journal article
Jazyk:English
Vydáno: 2005