Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.
<p><strong>Background</strong><br/>Cuprizone leads to demyelination of the corpus callosum (CC) and activates progenitor cells in the adjacent subventricular zone (SVZ), a stem cell niche which contributes to remyelination. The healthy SVZ contains semi-activated microglia an...
Main Authors: | Hillis, J, Davies, J, Mundim, M, Al-Dalahmah, O, Szele, F |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2016
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