Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.

<p><strong>Background</strong><br/>Cuprizone leads to demyelination of the corpus callosum (CC) and activates progenitor cells in the adjacent subventricular zone (SVZ), a stem cell niche which contributes to remyelination. The healthy SVZ contains semi-activated microglia an...

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Detalles Bibliográficos
Autores principales: Hillis, J, Davies, J, Mundim, M, Al-Dalahmah, O, Szele, F
Formato: Journal article
Lenguaje:English
Publicado: BioMed Central 2016