Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans.

Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans.

The non-heme ferrous dependent oxidase isopenicillin N synthase (IPNS) catalyses the biosynthesis of isopenicillin N from a tripeptide substrate. The crystal structure of Aspergillus nidulans IPNS complexed to manganese reveals a six co-ordinate metal ligated by two water molecules and four protein...

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Autors principals:	Sami, M, Brown, T, Roach, P, Schofield, C, Baldwin, J
Format:	Journal article
Idioma:	English
Publicat:	1997

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