Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans.
The non-heme ferrous dependent oxidase isopenicillin N synthase (IPNS) catalyses the biosynthesis of isopenicillin N from a tripeptide substrate. The crystal structure of Aspergillus nidulans IPNS complexed to manganese reveals a six co-ordinate metal ligated by two water molecules and four protein...
| Главные авторы: | , , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
1997
|