C1q and tumor necrosis factor superfamily: modularity and versatility.

C1q is the target recognition protein of the classical complement pathway and a major connecting link between innate and acquired immunity. As a charge pattern recognition molecule of innate immunity, C1q can engage a broad range of ligands via its globular (gC1q) domain and modulate immune cells, p...

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Detalles Bibliográficos
Main Authors: Kishore, U, Gaboriaud, C, Waters, P, Shrive, A, Greenhough, T, Reid, K, Sim, R, Arlaud, G
Formato: Journal article
Idioma:English
Publicado: 2004