Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Fairclough, R, Potter, A, Powell, D, Squire, S, Bland, M, Bareja, A, Tinsley, J, Davies, K
Μορφή:	Conference item
Έκδοση:	2008

Παρόμοια τεκμήρια

Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy
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Έκδοση: (2012)

Utrophin in the therapy of Duchenne Muscular Dystrophy
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Έκδοση: (2006)

Utrophin upregulation in Duchenne muscular dystrophy.
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Utrophin upregulation and microRNAs - two avenues of Duchenne muscular dystrophy therapy research
ανά: Bareja, A
Έκδοση: (2011)

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
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Έκδοση: (2014)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
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Έκδοση: (2019)

Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.
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Έκδοση: (2011)

Progress in therapy for Duchenne muscular dystrophy.
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Έκδοση: (2011)

Progress in therapy for Duchenne muscular dystrophy
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Έκδοση: (2011)

Utrophin upregulation in DMD therapy: current status and new tools for the future
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Έκδοση: (2011)

The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
ανά: Perkins, K, κ.ά.
Έκδοση: (2002)

Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
ανά: Tinsley, J, κ.ά.
Έκδοση: (2013)

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
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Expression of different isoforms of utrophin in human muscle; potentials for therapy of Duchenne muscular dystrophy
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Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.
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Utrophin in therapy of Duchenne muscular distrophy
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Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
ανά: Janghra, N, κ.ά.
Έκδοση: (2016)

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.
ανά: Narinder Janghra, κ.ά.
Έκδοση: (2016-01-01)

Mechanism of action studies of the utrophin modulator ezutromid for the treatment of Duchenne muscular dystrophy
ανά: Wilkinson, I
Έκδοση: (2019)

Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy
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Έκδοση: (2022-11-01)

Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
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Έκδοση: (2018)

From diagnosis to therapy in Duchenne muscular dystrophy
ανά: Babbs, A, κ.ά.
Έκδοση: (2020)

Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches.
ανά: Fairclough, R, κ.ά.
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Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation
ανά: Fairclough, R, κ.ά.
Έκδοση: (2010)

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.
ανά: Meghna Pant, κ.ά.
Έκδοση: (2015-01-01)

Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy.
ανά: Fairclough, R, κ.ά.
Έκδοση: (2012)

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
ανά: Perkins, K, κ.ά.
Έκδοση: (2001)

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
ανά: Tinsley, J, κ.ά.
Έκδοση: (2011)

Safety, Tolerability, and Pharmacokinetics of SMT C1100, a 2-Arylbenzoxazole Utrophin Modulator, following Single- and Multiple-Dose Administration to Pediatric Patients with Duchenne Muscular Dystrophy.
ανά: Valeria Ricotti, κ.ά.
Έκδοση: (2016-01-01)

Second-generation compound for the modulation of utrophin in the therapy of DMD
ανά: Guiraud, S, κ.ά.
Έκδοση: (2015)

Regenerative biomarkers for Duchenne muscular dystrophy
ανά: Guiraud, S, κ.ά.
Έκδοση: (2019)

Duchenne Muscular Dystrophy
ανά: J Gordon Millichap
Έκδοση: (1989-05-01)

Regenerative biomarkers for Duchenne muscular dystrophy
ανά: Simon Guiraud, κ.ά.
Έκδοση: (2019-01-01)

Therapeutic approaches for Duchenne muscular dystrophy
ανά: Roberts, TC, κ.ά.
Έκδοση: (2023)

PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
ανά: Kasturi Sengupta, κ.ά.
Έκδοση: (2020-12-01)

Nitric Oxide and l-Arginine Cause an Accumulation of Utrophin at the Sarcolemma: A Possible Compensation for Dystrophin Loss in Duchenne Muscular Dystrophy
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Έκδοση: (1999-12-01)

Duchenne muscular dystrophy - past, present and future
ανά: Davies, K
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Cardiac therapies for Duchenne muscular dystrophy
ανά: Md Nur Ahad Shah, κ.ά.
Έκδοση: (2023-07-01)

Rehabilitation therapy of Duchenne muscular dystrophy
ανά: Cheng ZHANG, κ.ά.
Έκδοση: (2012-06-01)

Pharmacological advances for treatment in Duchenne muscular dystrophy
ανά: Guiraud, S, κ.ά.
Έκδοση: (2017)