Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Fairclough, R, Potter, A, Powell, D, Squire, S, Bland, M, Bareja, A, Tinsley, J, Davies, K
Formáid:	Conference item
Foilsithe / Cruthaithe:	2008

Míreanna comhchosúla

Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2012)

Utrophin in the therapy of Duchenne Muscular Dystrophy
de réir: Potter, A, et al.
Foilsithe / Cruthaithe: (2006)

Utrophin upregulation in Duchenne muscular dystrophy.
de réir: Hirst, R, et al.
Foilsithe / Cruthaithe: (2005)

Utrophin upregulation and microRNAs - two avenues of Duchenne muscular dystrophy therapy research
de réir: Bareja, A
Foilsithe / Cruthaithe: (2011)

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2014)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
de réir: Guiraud, S, et al.
Foilsithe / Cruthaithe: (2019)

Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.
de réir: Chancellor, DR, et al.
Foilsithe / Cruthaithe: (2011)

Progress in therapy for Duchenne muscular dystrophy.
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2011)

Progress in therapy for Duchenne muscular dystrophy
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2011)

Utrophin upregulation in DMD therapy: current status and new tools for the future
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2011)

The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
de réir: Perkins, K, et al.
Foilsithe / Cruthaithe: (2002)

Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
de réir: Tinsley, J, et al.
Foilsithe / Cruthaithe: (2013)

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
de réir: Perkins, K, et al.
Foilsithe / Cruthaithe: (2000)

Expression of different isoforms of utrophin in human muscle; potentials for therapy of Duchenne muscular dystrophy
de réir: Sewry, C, et al.
Foilsithe / Cruthaithe: (2004)

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.
de réir: Griffin, J, et al.
Foilsithe / Cruthaithe: (2002)

Utrophin in therapy of Duchenne muscular distrophy
de réir: Fisher, R
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Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
de réir: Janghra, N, et al.
Foilsithe / Cruthaithe: (2016)

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.
de réir: Narinder Janghra, et al.
Foilsithe / Cruthaithe: (2016-01-01)

Mechanism of action studies of the utrophin modulator ezutromid for the treatment of Duchenne muscular dystrophy
de réir: Wilkinson, I
Foilsithe / Cruthaithe: (2019)

Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy
de réir: Ruo Wu, et al.
Foilsithe / Cruthaithe: (2022-11-01)

Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
de réir: Perkins, K, et al.
Foilsithe / Cruthaithe: (2018)

From diagnosis to therapy in Duchenne muscular dystrophy
de réir: Babbs, A, et al.
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Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches.
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2013)

Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation
de réir: Fairclough, R, et al.
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Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.
de réir: Meghna Pant, et al.
Foilsithe / Cruthaithe: (2015-01-01)

Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy.
de réir: Fairclough, R, et al.
Foilsithe / Cruthaithe: (2012)

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
de réir: Perkins, K, et al.
Foilsithe / Cruthaithe: (2001)

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
de réir: Tinsley, J, et al.
Foilsithe / Cruthaithe: (2011)

Safety, Tolerability, and Pharmacokinetics of SMT C1100, a 2-Arylbenzoxazole Utrophin Modulator, following Single- and Multiple-Dose Administration to Pediatric Patients with Duchenne Muscular Dystrophy.
de réir: Valeria Ricotti, et al.
Foilsithe / Cruthaithe: (2016-01-01)

Second-generation compound for the modulation of utrophin in the therapy of DMD
de réir: Guiraud, S, et al.
Foilsithe / Cruthaithe: (2015)

Regenerative biomarkers for Duchenne muscular dystrophy
de réir: Guiraud, S, et al.
Foilsithe / Cruthaithe: (2019)

Duchenne Muscular Dystrophy
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Regenerative biomarkers for Duchenne muscular dystrophy
de réir: Simon Guiraud, et al.
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Therapeutic approaches for Duchenne muscular dystrophy
de réir: Roberts, TC, et al.
Foilsithe / Cruthaithe: (2023)

PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
de réir: Kasturi Sengupta, et al.
Foilsithe / Cruthaithe: (2020-12-01)

Nitric Oxide and l-Arginine Cause an Accumulation of Utrophin at the Sarcolemma: A Possible Compensation for Dystrophin Loss in Duchenne Muscular Dystrophy
de réir: Emmanuel Chaubourt, et al.
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Duchenne muscular dystrophy - past, present and future
de réir: Davies, K
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Cardiac therapies for Duchenne muscular dystrophy
de réir: Md Nur Ahad Shah, et al.
Foilsithe / Cruthaithe: (2023-07-01)

Rehabilitation therapy of Duchenne muscular dystrophy
de réir: Cheng ZHANG, et al.
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Pharmacological advances for treatment in Duchenne muscular dystrophy
de réir: Guiraud, S, et al.
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