Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Evaluation of novel compounds for upregulation of utrophin in animal models of Duchenne muscular dystrophy therapy

Bibliografische gegevens
Hoofdauteurs:	Fairclough, R, Potter, A, Powell, D, Squire, S, Bland, M, Bareja, A, Tinsley, J, Davies, K
Formaat:	Conference item
Gepubliceerd in:	2008

Gelijkaardige items

Identification of new chemical compounds with upregulate utrophin for the therapy of Duchenne muscular dystrophy
door: Fairclough, R, et al.
Gepubliceerd in: (2012)

Utrophin in the therapy of Duchenne Muscular Dystrophy
door: Potter, A, et al.
Gepubliceerd in: (2006)

Utrophin upregulation in Duchenne muscular dystrophy.
door: Hirst, R, et al.
Gepubliceerd in: (2005)

Utrophin upregulation and microRNAs - two avenues of Duchenne muscular dystrophy therapy research
door: Bareja, A
Gepubliceerd in: (2011)

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
door: Fairclough, R, et al.
Gepubliceerd in: (2014)

The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy
door: Guiraud, S, et al.
Gepubliceerd in: (2019)

Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.
door: Chancellor, DR, et al.
Gepubliceerd in: (2011)

Progress in therapy for Duchenne muscular dystrophy.
door: Fairclough, R, et al.
Gepubliceerd in: (2011)

Progress in therapy for Duchenne muscular dystrophy
door: Fairclough, R, et al.
Gepubliceerd in: (2011)

Utrophin upregulation in DMD therapy: current status and new tools for the future
door: Fairclough, R, et al.
Gepubliceerd in: (2011)

The role of utrophin in the potential therapy of Duchenne muscular dystrophy.
door: Perkins, K, et al.
Gepubliceerd in: (2002)

Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
door: Tinsley, J, et al.
Gepubliceerd in: (2013)

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
door: Perkins, K, et al.
Gepubliceerd in: (2000)

Expression of different isoforms of utrophin in human muscle; potentials for therapy of Duchenne muscular dystrophy
door: Sewry, C, et al.
Gepubliceerd in: (2004)

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy.
door: Griffin, J, et al.
Gepubliceerd in: (2002)

Utrophin in therapy of Duchenne muscular distrophy
door: Fisher, R
Gepubliceerd in: (2001)

Correlation of utrophin levels with the dystrophin protein complex and muscle fibre regeneration in Duchenne and Becker muscular dystrophy muscle biopsies
door: Janghra, N, et al.
Gepubliceerd in: (2016)

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.
door: Narinder Janghra, et al.
Gepubliceerd in: (2016-01-01)

Mechanism of action studies of the utrophin modulator ezutromid for the treatment of Duchenne muscular dystrophy
door: Wilkinson, I
Gepubliceerd in: (2019)

Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy
door: Ruo Wu, et al.
Gepubliceerd in: (2022-11-01)

Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin-deficient mice and Duchenne muscular dystrophy
door: Perkins, K, et al.
Gepubliceerd in: (2018)

From diagnosis to therapy in Duchenne muscular dystrophy
door: Babbs, A, et al.
Gepubliceerd in: (2020)

Therapy for Duchenne muscular dystrophy: renewed optimism from genetic approaches.
door: Fairclough, R, et al.
Gepubliceerd in: (2013)

Utrophin luciferase knock-in mouse model for in vivo assessment of drug efficacy in preclinical trials for utrophin upregulation
door: Fairclough, R, et al.
Gepubliceerd in: (2010)

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.
door: Meghna Pant, et al.
Gepubliceerd in: (2015-01-01)

Pharmacologically targeting the primary defect and downstream pathology in Duchenne muscular dystrophy.
door: Fairclough, R, et al.
Gepubliceerd in: (2012)

The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy.
door: Perkins, K, et al.
Gepubliceerd in: (2001)

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
door: Tinsley, J, et al.
Gepubliceerd in: (2011)

Safety, Tolerability, and Pharmacokinetics of SMT C1100, a 2-Arylbenzoxazole Utrophin Modulator, following Single- and Multiple-Dose Administration to Pediatric Patients with Duchenne Muscular Dystrophy.
door: Valeria Ricotti, et al.
Gepubliceerd in: (2016-01-01)

Second-generation compound for the modulation of utrophin in the therapy of DMD
door: Guiraud, S, et al.
Gepubliceerd in: (2015)

Regenerative biomarkers for Duchenne muscular dystrophy
door: Guiraud, S, et al.
Gepubliceerd in: (2019)

Duchenne Muscular Dystrophy
door: J Gordon Millichap
Gepubliceerd in: (1989-05-01)

Regenerative biomarkers for Duchenne muscular dystrophy
door: Simon Guiraud, et al.
Gepubliceerd in: (2019-01-01)

Therapeutic approaches for Duchenne muscular dystrophy
door: Roberts, TC, et al.
Gepubliceerd in: (2023)

PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)
door: Kasturi Sengupta, et al.
Gepubliceerd in: (2020-12-01)

Nitric Oxide and l-Arginine Cause an Accumulation of Utrophin at the Sarcolemma: A Possible Compensation for Dystrophin Loss in Duchenne Muscular Dystrophy
door: Emmanuel Chaubourt, et al.
Gepubliceerd in: (1999-12-01)

Duchenne muscular dystrophy - past, present and future
door: Davies, K
Gepubliceerd in: (2002)

Cardiac therapies for Duchenne muscular dystrophy
door: Md Nur Ahad Shah, et al.
Gepubliceerd in: (2023-07-01)

Rehabilitation therapy of Duchenne muscular dystrophy
door: Cheng ZHANG, et al.
Gepubliceerd in: (2012-06-01)

Pharmacological advances for treatment in Duchenne muscular dystrophy
door: Guiraud, S, et al.
Gepubliceerd in: (2017)