Screening for inhibitors of and novel proteins within the homologous recombination DNA repair pathway
The homologous recombination (HR) pathway of DNA repair is essential for the faithful repair of double-stranded DNA breaks (DSBs) in all organisms and as such helps maintain genomic stability. Furthermore, HR is instrumental in the cellular response to exogenous DNA damaging agents such as those use...
Main Author: | Kingham, G |
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Other Authors: | Helleday, T |
Format: | Thesis |
Language: | English |
Published: |
2012
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Subjects: |
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