Viral mutation and substitution: units and levels.
Viruses evolve within a hierarchy of organisational levels, from cells to host species. We discuss how these nested population structures complicate the meaning and interpretation of two apparently simple evolutionary concepts: mutation rate and substitution rate. We discuss the units in which these...
Main Authors: | Belshaw, R, Sanjuán, R, Pybus, O |
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Format: | Journal article |
Language: | English |
Published: |
2011
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