Autophagy and hypoxia in colonic adenomas related to aggressive features.
AIM: The study investigated whether autophagic activity and hypoxia parallel the adenoma-carcinoma sequence. METHOD: The study comprised 120 tubular adenomas with high-grade dysplasia, including 22 with questionable evidence of invasion, 37 with definite stromal invasion and 29 with severely dysplas...
Main Authors: | Giatromanolaki, A, Koukourakis, M, Koutsopoulos, A, Harris, A, Gatter, K, Sivridis, E |
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Format: | Journal article |
Language: | English |
Published: |
2013
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