Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid.
(+)-Steviamine, the enantiomer of the natural (-)-steviamine, and its corresponding C5 epimer have been synthesized from the D-ribose-derived cyclic nitrone. (-)-Steviamine was found to be the first naturally occurring iminosugar that causes any inhibition of alpha-galactosaminidases.
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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| _version_ | 1797100093220847616 |
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| author | Hu, X Bartholomew, B Nash, R Wilson, F Fleet, G Nakagawa, S Kato, A Jia, Y van Well, R Yu, C |
| author_facet | Hu, X Bartholomew, B Nash, R Wilson, F Fleet, G Nakagawa, S Kato, A Jia, Y van Well, R Yu, C |
| author_sort | Hu, X |
| collection | OXFORD |
| description | (+)-Steviamine, the enantiomer of the natural (-)-steviamine, and its corresponding C5 epimer have been synthesized from the D-ribose-derived cyclic nitrone. (-)-Steviamine was found to be the first naturally occurring iminosugar that causes any inhibition of alpha-galactosaminidases. |
| first_indexed | 2024-03-07T05:32:54Z |
| format | Journal article |
| id | oxford-uuid:e2e16cb5-2bbe-4d42-a305-b58afa6806d5 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:32:54Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:e2e16cb5-2bbe-4d42-a305-b58afa6806d52022-03-27T10:04:47ZSynthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e2e16cb5-2bbe-4d42-a305-b58afa6806d5EnglishSymplectic Elements at Oxford2010Hu, XBartholomew, BNash, RWilson, FFleet, GNakagawa, SKato, AJia, Yvan Well, RYu, C(+)-Steviamine, the enantiomer of the natural (-)-steviamine, and its corresponding C5 epimer have been synthesized from the D-ribose-derived cyclic nitrone. (-)-Steviamine was found to be the first naturally occurring iminosugar that causes any inhibition of alpha-galactosaminidases. |
| spellingShingle | Hu, X Bartholomew, B Nash, R Wilson, F Fleet, G Nakagawa, S Kato, A Jia, Y van Well, R Yu, C Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title | Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title_full | Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title_fullStr | Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title_full_unstemmed | Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title_short | Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid. |
| title_sort | synthesis and glycosidase inhibition of the enantiomer of steviamine the first example of a new class of indolizidine alkaloid |
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