Atomistic studies of the dynamics of P-glycoprotein and its ligands

<p>A signifficant obstacle facing the healthcare industry is the phenomenon of multidrug resistance (MDR) in which a cell acquires simultaneous resistance to many unrelated drugs that it has never been exposed to. At the molecular level, MDR can be characterised by a reduction of intracellular...

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Bibliographic Details
Main Authors: Ma, J, Jerome Ho Yin Ma
Other Authors: Biggin, P
Format: Thesis
Language:English
Published: 2013
Subjects: