Targeted delivery of galunisertib using machine perfusion reduces fibrogenesis in an integrated ex vivo renal transplant and fibrogenesis model
<p><strong>Background and Purpose:</strong> Fibrosis in kidney allografts is a major post-transplant complication that contributes to graft failure. Lately, multiple potent inhibitors of fibrosis-related pathways have been developed such as galunisertib, an inhibitor of the transfo...
Main Authors: | van Leeuwen, LL, Ruigrok, MJR, Kessler, BM, Leuvenink, HGD, Olinga, P |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
Wiley
2023
|
פריטים דומים
-
Fibrogenesis imperfecta ossium.
מאת: Carr, A, et al.
יצא לאור: (1995) -
Doxycycline alters the porcine renal proteome and degradome during hypothermic machine perfusion
מאת: van Leeuwen, L, et al.
יצא לאור: (2022) -
Epithelial-Mesenchymal Transition and its Role in Renal Fibrogenesis
מאת: Brij Mohan Kumar Singh, et al.
יצא לאור: (2022-08-01) -
Fibrogenesis in Human Mucosa and Muscularis Precision-Cut Intestinal Slices
מאת: Carin Biel, et al.
יצא לאור: (2024-06-01) -
Role of redoximiRs in fibrogenesis
מאת: Marta Fierro-Fernández, et al.
יצא לאור: (2016-04-01)