Comparison of different therapies for neonatal diabetes – glibenclamide vs insulin
<p>Gain-of-function mutations in the Kir6.2 and SUR subunits of the KATP channel are associated with neonatal diabetes (ND). I used a mouse model selectively expressing the Kir6.2-V59M mutation in pancreatic β-cells (inducible iβ-V59M) to compare the effects of sulphonylurea and insulin therap...
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| Format: | Thesis |
| Language: | English |
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2012
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