Comparison of different therapies for neonatal diabetes – glibenclamide vs insulin

Comparison of different therapies for neonatal diabetes – glibenclamide vs insulin

<p>Gain-of-function mutations in the Kir6.2 and SUR subunits of the KATP channel are associated with neonatal diabetes (ND). I used a mouse model selectively expressing the Kir6.2-V59M mutation in pancreatic β-cells (inducible iβ-V59M) to compare the effects of sulphonylurea and insulin therap...

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Dettagli Bibliografici
Autore principale:	Iberl, M
Altri autori:	Ashcroft, F
Natura:	Tesi
Lingua:	English
Pubblicazione:	2012
Soggetti:	Genetics (life sciences) Medical Sciences Diabetes Physiology and anatomy

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