Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.

Medullary thymic epithelial cells (mTECs) are specialized for inducing central immunological tolerance to self-antigens. To accomplish this, mTECs must adopt a mature phenotype characterized by expression of the autoimmune regulator Aire, which activates the transcription of numerous genes encoding...

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Bibliographic Details
Main Authors:	Irla, M, Hugues, S, Gill, J, Nitta, T, Hikosaka, Y, Williams, I, Hubert, F, Scott, H, Takahama, Y, Holländer, G, Reith, W
Format:	Journal article
Language:	English
Published:	2008

Autoantigen-specific interactions with CD4+thymocytes control mature medullary thymic epithelial cell cellularity by Irla, M, Hugues, S, Gill, J, Nitta, T, Hikosaka, Y, Williams, I, Hubert, F, Scott, H, Takahama, Y, Hollaender, G, Reith, W

Published 2009

Journal article

Autoantigen-specific interactions with CD4+ thymocytes control mature medullary thymic epithelial cell cellularity.

Autoantigen-specific interactions with CD4+thymocytes control mature medullary thymic epithelial cell cellularity by Irla, M, Hugues, S, Gill, J, Nitta, T, Hikosaka, Y, Williams, I, Hubert, F, Scott, H, Takahama, Y, Hollaender, G, Reith, W

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