Latent inhibition in rats is abolished by NMDA-induced neuronal loss in the retrohippocampal region, but this lesion effect can be prevented by systemic haloperidol treatment.

Latent inhibition in rats is abolished by NMDA-induced neuronal loss in the retrohippocampal region, but this lesion effect can be prevented by systemic haloperidol treatment.

Latent inhibition (LI) refers to the retardation in learning about the significance of a neutral stimulus that results from its nonreinforced preexposure. There is evidence that electrolytic or aspiration lesions of the hippocampal formation can disrupt LI (see I. Weiner, 1990). It has been suggeste...

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Bibliografiske detaljer
Main Authors:	Yee, B, Feldon, J, Rawlins, J
Format:	Journal article
Sprog:	English
Udgivet:	1995

Lignende værker

Potentiation of amphetamine-induced locomotor activity following NMDA-induced retrohippocampal neuronal loss in the rat.
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Udgivet: (1995)

Cytotoxic lesions of the retrohippocampal region attenuate latent inhibition but spare the partial reinforcement extinction effect.
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The effects of NMDA-induced retrohippocampal lesions on performance of four spatial memory tasks known to be sensitive to hippocampal damage in the rat.
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HALOPERIDOL INCREASES LATENT INHIBITION IN HIGH SCHIZOTYPAL SUBJECTS
af: Williams, J, et al.
Udgivet: (1994)

Haloperidol enhances latent inhibition in visual tasks in healthy people.
af: Williams, J, et al.
Udgivet: (1997)

The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia.
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Activation of the retrohippocampal region in the rat causes dopamine release in the nucleus accumbens: disruption by fornix section.
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Selective cytotoxic lesions of the retrohippocampal region produce a mild deficit in social recognition memory.
af: Bannerman, D, et al.
Udgivet: (2002)

Antipsychotic drug effects in a model of schizophrenic attentional disorder: a randomized controlled trial of the effects of haloperidol on latent inhibition in healthy people.
af: Williams, J, et al.
Udgivet: (1996)

Electrolytic lesions of the nucleus accumbens in rats which abolish the PREE enhance the locomotor response to amphetamine.
af: Tai, C, et al.
Udgivet: (1991)

Both electrolytic and excitotoxic lesions of nucleus accumbens disrupt latent inhibition of learning in rats.
af: Tai, C, et al.
Udgivet: (1995)

Aspiration lesions of rat ventral hippocampus disinhibit responding in conditioned suppression or extinction, but spare latent inhibition and the partial reinforcement extinction effect.
af: Clark, A, et al.
Udgivet: (1992)

Haloperidol reduces stroop interference and increases negative priming in healthy people
af: Williams, J, et al.
Udgivet: (1996)

A neuroleptic-like effect of ceronapril on latent inhibition.
af: Weiner, I, et al.
Udgivet: (1992)

Rats' processing of visual scenes: effects of lesions to fornix, anterior thalamus, mamillary nuclei or the retrohippocampal region.
af: Gaffan, E, et al.
Udgivet: (2001)

Intravenous administration of haloperidol to healthy volunteers: lack of subjective effects but clear objective effects.
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Udgivet: (1997)

Deficits in latent inhibition induced by estradiol replacement are ameliorated by haloperidol treatment
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Latent inhibition is not reduced in drug-free patients with schizophrenia
af: Williams, J, et al.
Udgivet: (1996)

Differential involvement of the shell and core subterritories of the nucleus accumbens in latent inhibition and amphetamine-induced activity.
af: Weiner, I, et al.
Udgivet: (1996)

Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment.
af: Williams, J, et al.
Udgivet: (1998)

THE SIGMA-LIGAND BMY-14802 AS A POTENTIAL ANTIPSYCHOTIC - EVIDENCE FROM THE LATENT INHIBITION MODEL IN RATS
af: Weiner, I, et al.
Udgivet: (1995)

Dorsal bundle lesions do not affect latent inhibition of conditioned suppression.
af: Tsaltas, E, et al.
Udgivet: (1984)

The effects of hippocampal and fimbria-fornix lesions on prepulse inhibition.
af: Pouzet, B, et al.
Udgivet: (1999)

EFFECTS OF TOBACCO SMOKING, SCHIZOTYPY AND NUMBER OF PRE-EXPOSURES ON LATENT INHIBITION IN HEALTHY-SUBJECTS
af: Allan, L, et al.
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The influence of selective lesions to components of the hippocampal system on the orienting [correction of orientating] response, habituation and latent inhibition.
af: Oswald, C, et al.
Udgivet: (2002)

THE EFFECTS OF CHRONIC ADMINISTRATION OF CERONAPRIL ON THE PARTIAL-REINFORCEMENT EXTINCTION EFFECT AND LATENT INHIBITION IN RATS
af: Weiner, I, et al.
Udgivet: (1994)

Memory impairment and learning capacities in dorso-hippocampal lesioned rats: Methodological considerations.
af: Pouzet, B, et al.
Udgivet: (1998)

The effects of delaying reward on choice preference in rats with hippocampal or selective septal lesions.
af: Rawlins, J, et al.
Udgivet: (1985)

EFFECTS OF MEDIAL SEPTAL-LESIONS AND SMALL DORSAL FORNIX LESIONS ON PARTIAL-REINFORCEMENT EXTINCTION EFFECT
af: Feldon, J, et al.
Udgivet: (1977)

EFFECTS OF SMALL SEPTAL-LESIONS AND CHLORDIAZEPOXIDE ON SHOCK-INDUCED SUPRESSION OF BARPRESSING
af: Rawlins, J, et al.
Udgivet: (1977)

DRL PERFORMANCE IN RATS WITH MEDIAL OR LATERAL SEPTAL-LESIONS
af: Brookes, S, et al.
Udgivet: (1983)

Haloperidol
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Inhibition of ATP-sensitive potassium channels by haloperidol.
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Udgivet: (2004)

LATERAL SEPTAL-LESIONS, CHLORDIAZEPOXIDE INJECTIONS AND PARTIAL-REINFORCEMENT EXTINCTION EFFECT AT 2 TRAINING LENGTHS
af: Feldon, J, et al.
Udgivet: (1978)

Ventral hippocampal lesions affect anxiety but not spatial learning.
af: Bannerman, D, et al.
Udgivet: (2003)

Discrimination of response-contingent and response-independent shock by rats: effects of medial and lateral septal lesions and chlordiazepoxide.
af: Feldon, J, et al.
Udgivet: (1982)

EFFECTS OF LATERAL AND MEDIAL SEPTAL-LESIONS ON RESPONSE SUPPRESSION MAINTAINED BY RESPONSE-CONTINGENT AND RESPONSE-INDEPENDENT SHOCK
af: Feldon, J, et al.
Udgivet: (1982)

Hippocampal NMDA receptors are important for behavioural inhibition but not for encoding associative spatial memories.
af: Taylor, A, et al.
Udgivet: (2014)

THE EFFECTS OF HIPPOCAMPAL-LESIONS VARY WITH INTER-EVENT INTERVAL
af: Rawlins, J, et al.
Udgivet: (1984)

ADENOSINE RECEPTOR INHIBITION ABOLISHES REMOTE ISCHAEMIC PRECONDITIONING IN HUMANS
af: Contractor, H, et al.
Udgivet: (2009)