The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.

The burden of Plasmodium falciparum malaria has been estimated traditionally in terms of infections and mortality. Neurocognitive sequelae have recently been identified that add to the burden caused by this parasite. We have attempted to provide estimates of the neurocognitive burden based upon more...

Full description

Bibliographic Details
Main Authors: Mung'Ala-Odera, V, Snow, R, Newton, C
Format: Journal article
Language:English
Published: 2004
_version_ 1826301493712519168
author Mung'Ala-Odera, V
Snow, R
Newton, C
author_facet Mung'Ala-Odera, V
Snow, R
Newton, C
author_sort Mung'Ala-Odera, V
collection OXFORD
description The burden of Plasmodium falciparum malaria has been estimated traditionally in terms of infections and mortality. Neurocognitive sequelae have recently been identified that add to the burden caused by this parasite. We have attempted to provide estimates of the neurocognitive burden based upon more recent estimates of the population at risk and a detailed review of published studies in sub-Saharan Africa. There is little data on which to estimate the burden, and considerable limitations in extracting the data from the published studies to provide these estimates. However, we estimate that at least 1,300-7,800 children will have neurologic sequelae following cerebral malaria in stable endemic areas per year. The figure is likely to be considerably higher, since these estimates do not include neurocognitive impairment following non-cerebral malaria in children or adults in stable endemic areas, or populations in low stable or epidemic areas.
first_indexed 2024-03-07T05:33:16Z
format Journal article
id oxford-uuid:e3010eb8-b458-4203-bc5d-6012dd5ca78a
institution University of Oxford
language English
last_indexed 2024-03-07T05:33:16Z
publishDate 2004
record_format dspace
spelling oxford-uuid:e3010eb8-b458-4203-bc5d-6012dd5ca78a2022-03-27T10:05:41ZThe burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:e3010eb8-b458-4203-bc5d-6012dd5ca78aEnglishSymplectic Elements at Oxford2004Mung'Ala-Odera, VSnow, RNewton, CThe burden of Plasmodium falciparum malaria has been estimated traditionally in terms of infections and mortality. Neurocognitive sequelae have recently been identified that add to the burden caused by this parasite. We have attempted to provide estimates of the neurocognitive burden based upon more recent estimates of the population at risk and a detailed review of published studies in sub-Saharan Africa. There is little data on which to estimate the burden, and considerable limitations in extracting the data from the published studies to provide these estimates. However, we estimate that at least 1,300-7,800 children will have neurologic sequelae following cerebral malaria in stable endemic areas per year. The figure is likely to be considerably higher, since these estimates do not include neurocognitive impairment following non-cerebral malaria in children or adults in stable endemic areas, or populations in low stable or epidemic areas.
spellingShingle Mung'Ala-Odera, V
Snow, R
Newton, C
The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title_full The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title_fullStr The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title_full_unstemmed The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title_short The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.
title_sort burden of the neurocognitive impairment associated with plasmodium falciparum malaria in sub saharan africa
work_keys_str_mv AT mungalaoderav theburdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica
AT snowr theburdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica
AT newtonc theburdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica
AT mungalaoderav burdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica
AT snowr burdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica
AT newtonc burdenoftheneurocognitiveimpairmentassociatedwithplasmodiumfalciparummalariainsubsaharanafrica