A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Elucidation of mechanisms underlying the increased androgen receptor (AR) activity and subsequent development of aggressive prostate cancer (PrCa) is pivotal in developing new therapies. Using a systems biology approach, we interrogated the AR-regulated proteome and identified PDZ binding kinase (PB...

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Hlavní autoři: Warren, A, Massie, C, Watt, K, Luko, K, Orafidiya, F, Selth, L, Mohammed, H, Chohan, B, Menon, S, Baridi, A, Zhao, W, Escriu, C, Pungsrinont, T, D'Santos, C, Yang, X, Taylor, C, Qureshi, A, Zecchini, V, Shaw, G, Dehm, S, Mills, I, Carroll, J, Tilley, W, McEwan, I, Baniahmad, A, Neal, D, Asim, M
Médium: Journal article
Jazyk:English
Vydáno: Springer Nature 2018

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