Characterisation of a novel gene-targeted model for PRKAG2 disease
<p>AMP-activated protein kinase (AMPK) is an evolutionarily highly-conserved serine/threonine kinase that acts as a cellular energy sensor and integrator of metabolic signals at both the cellular and whole-body level. Interest in its cardiac role stemmed from the discovery that dominant mutati...
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Format: | Thesis |
Idioma: | English |
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2013
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