Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
Organisms must respond to hypoxia to preserve oxygen homeostasis. We identify a thiol oxidase, previously assigned as cysteamine (2-aminoethanethiol) dioxygenase (ADO), as a low oxygen affinity (high-KmO2) amino-terminal cysteine dioxygenase that transduces the oxygen-regulated stability of proteins...
Main Authors: | Masson, N, Keeley, T, Giuntoli, B, White, M, Puerta, M, Perata, P, Hopkinson, R, Flashman, E, Licausi, F, Ratcliffe, P |
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Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2019
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