Possible footprints of APOBEC3F and/or other APOBEC3 deaminases, but not APOBEC3G, on HIV-1 from patients with acute/early and chronic infections.
UNLABELLED: Members of the apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like-3 (APOBEC3) innate cellular cytidine deaminase family, particularly APOBEC3F and APOBEC3G, can cause extensive and lethal G-to-A mutations in HIV-1 plus-strand DNA (termed hypermutation). It is unclear if APOB...
Main Authors: | Armitage, A, Deforche, K, Welch, J, Van Laethem, K, Camacho, R, Rambaut, A, Iversen, A |
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Format: | Journal article |
Language: | English |
Published: |
2014
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