Possible footprints of APOBEC3F and/or other APOBEC3 deaminases, but not APOBEC3G, on HIV-1 from patients with acute/early and chronic infections.

UNLABELLED: Members of the apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like-3 (APOBEC3) innate cellular cytidine deaminase family, particularly APOBEC3F and APOBEC3G, can cause extensive and lethal G-to-A mutations in HIV-1 plus-strand DNA (termed hypermutation). It is unclear if APOB...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Armitage, A, Deforche, K, Welch, J, Van Laethem, K, Camacho, R, Rambaut, A, Iversen, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2014