Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration
To differentiate the unique and overlapping functions of LFA-1 and Mac-1, LFA-1-deficient mice were developed by targeted homologous recombination in embryonic stem cells, and neutrophil function was compared in vitro and in vivo with Mac-1-deficient, CD18-deficient, and wild-type mice. LFA-1-defici...
Главные авторы: | Ding, Z, Babensee, J, Simon, S, Lu, H, Perrard, J, Bullard, D, Dai, X, Bromley, S, Dustin, M, Entman, M, Smith, C, Ballantyne, C |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
American Association of Immunologists, Inc.
1999
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