Vascular effects dominate solid tumor response to treatment with combretastatin A-4-phosphate.

Vascular-targeted therapeutics are increasingly used in the clinic. However, less is known about the direct response of tumor cells to these agents. We have developed a combretastatin-A-4-phosphate (CA4P) resistant variant of SW1222 human colorectal carcinoma cells to examine the relative importance...

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Bibliographic Details
Main Authors: Lunt, S, Akerman, S, Hill, S, Fisher, M, Wright, V, Reyes-Aldasoro, C, Tozer, G, Kanthou, C
Format: Journal article
Language:English
Published: 2011