Chemo-enzymatic synthesis of bicyclic gamma-lactams using clavaminic acid synthase
Incubation of the γ-lactam analogue of proclavaminic acid, (±)-threo-5-amino-3-hydroxy-2-(1'-aza-2'-oxocyclopentyl) acid, led to production of two bicyclic γ-lactam products.
Auteurs principaux: | , , , , , , , |
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Format: | Journal article |
Publié: |
1997
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