Design of a chemical probe for the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins

Design of a chemical probe for the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins

The bromodomain and plant homeodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of histone acetyltransferases of the MYST family to chromatin. Here, we describe NI-57 (16) as new pan-BRPF chemical probe of the bromodomain (BRD) of the BRPFs. Inhibitor 16...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Igoe, N, Bayle, E, Tallant, C, Fedorov, O, Meier, J, Savitsky, P, Rogers, C, Morias, Y, Scholze, S, Boyd, H, Cunoosamy, D, Andrews, D, Cheasty, A, Brennan, P, Müller, S, Knapp, S, Fish, P
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: American Chemical Society 2017

অনুরূপ উপাদানগুলি

অনুরূপ উপাদানগুলি