Protein inhibitor of NOS1 plays a central role in the regulation of NOS1 activity in human dilated hearts
An essential factor for the production of nitric oxide by nitric oxide synthase 1 (NOS1), major modulator of cardiac function, is the cofactor tetrahydrobiopterin (BH4). BH4 is regulated by GTP cyclohydrolase 1, the rate-limiting enzyme in BH4 biosynthesis which catalyses the formation of dihydroneo...
| Main Authors: | , , , , , , , , |
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| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
Nature Publishing Group
2016
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