Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue

Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue

Human leukocyte antigen (HLA)-B27 (B27) is the strongest genetic factor associated with development of Ankylosing Spondylitis and other spondyloarthropathies (SpA), yet the role it plays in disease pathogenesis remains unclear. We investigated the expression of potentially pathogenic non-conventiona...

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Bibliografiske detaljer
Main Authors:	Rysnik, O, McHugh, K, van Duivenvoorde, L, van Tok, M, Guggino, G, Taurog, J, Kollnberger, S, Ciccia, F, Baeten, D, Bowness, P
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 2016

Lignende værker

Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue
af: Rysnik, O, et al.
Udgivet: (2016)

Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue
af: Oliwia Rysnik, et al.
Udgivet: (2016-12-01)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
af: Rysnik, O, et al.
Udgivet: (2012)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
af: Rysnik, O, et al.
Udgivet: (2013)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
af: Rysnik, O, et al.
Udgivet: (2012)

Innate Immune Activation Can Trigger Experimental Spondyloarthritis in HLA-B27/Huβ2m Transgenic Rats
af: Melissa N. van Tok, et al.
Udgivet: (2017-08-01)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
af: Rysnik, O, et al.
Udgivet: (2013)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
af: Wong-Baeza, I, et al.
Udgivet: (2011)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
af: Kollnberger, S, et al.
Udgivet: (2012)

Paradoxical Augmentation of Experimental Spondyloarthritis by RORC Inhibition in HLA-B27 Transgenic Rats
af: Melissa N. van Tok, et al.
Udgivet: (2021-09-01)

The role of HLA-B27 in the pathogenesis of spondyloarthritis
af: McHugh, K
Udgivet: (2011)

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
af: Hatano, H, et al.
Udgivet: (2013)

The expression patterns of non-classical and classical forms of HLA-B27 in spondyloarthritis
af: Rysnik, O
Udgivet: (2015)

The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of spondyloarthritis
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Udgivet: (2007)

The role of HLA-B27 in spondyloarthritis.
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Udgivet: (1999)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
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Udgivet: (2014)

HD6: a novel monoclonal antibody that recognises a subset of HLA-B27 molecules strongly implicated in spondyloarthritis disease pathogenesis
af: McHugh, K, et al.
Udgivet: (2011)

HD6: A NOVEL MONOCLONAL ANTIBODY THAT RECOGNISES A SUBSET OF HLA-B27 MOLECULES STRONGLY IMPLICATED IN SPONDYLOARTHRITIS DISEASE PATHOGENESIS
af: McHugh, K, et al.
Udgivet: (2011)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
af: Giles, J, et al.
Udgivet: (2008)

The role of B27 heavy chain dimer immune receptor interactions in spondyloarthritis.
af: Kollnberger, S, et al.
Udgivet: (2009)

HLA-B27: natural function and pathogenic role in spondyloarthritis.
af: McMichael, A, et al.
Udgivet: (2002)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
af: McHugh, K, et al.
Udgivet: (2008)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
af: Kollnberger, S, et al.
Udgivet: (2004)

Role of Subclinical Gut Inflammation in the Pathogenesis of Spondyloarthritis
af: Aroldo Rizzo, et al.
Udgivet: (2018-05-01)

HLA-B27 and KIR3DL2 Interactions Promote The Differentiation and Survival Of Proinflammatory T Cells In Spondyloarthritis
af: Ridley, A, et al.
Udgivet: (2013)

The role of cell surface HLA-B27 heavy chain homodimer interactions with NK receptors in the pathogenesis of spondyloarthritis
af: Kollnberger, S
Udgivet: (2005)

HLA-B27 FORMS HEAVY CHAIN HOMODIMERS IN VITRO AND IN VIVO THAT BIND TO CELLULAR RECEPTORS INCLUDING LILR AND KIR FAMILY MEMBERS
af: McHugh, K, et al.
Udgivet: (2010)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
af: Giles, J, et al.
Udgivet: (2010)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
af: Shaw, J, et al.
Udgivet: (2013)

Supplementary figures for "Inhibiting HLA-B27 homdimer-driven immune cell inflammation in Spondyloarthritis"
af: Bowness, P
Udgivet: (2012)

KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis.
af: Wong-Baeza, I, et al.
Udgivet: (2013)

KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis.
af: Wong-Baeza, I, et al.
Udgivet: (2013)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

Factors determining the cell surface expression of a novel HLA-B27 epitope
af: McHugh, K, et al.
Udgivet: (2010)

The link between HLA-B27 and SpA--new ideas on an old problem.
af: McHugh, K, et al.
Udgivet: (2012)

HLA-B*2709, A SUBTYPE NOT ASSOCIATED WITH ANKYLOSING SPONDYLITIS, FORMS FEWER HOMODIMERS THAN HLA-B*2705
af: Giles, J, et al.
Udgivet: (2010)

The Initiation, but Not the Persistence, of Experimental Spondyloarthritis Is Dependent on Interleukin-23 Signaling
af: Melissa N. van Tok, et al.
Udgivet: (2018-07-01)

mTOR Blockade by Rapamycin in Spondyloarthritis: Impact on Inflammation and New Bone Formation in vitro and in vivo
af: Sijia Chen, et al.
Udgivet: (2020-02-01)

Functional characterisation of HLA-B27 in autoimmunity
af: Kollnberger, S, et al.
Udgivet: (2001)