A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI.
Human and murine cerebral malaria are associated with elevated levels of cytokines in the brain and adherence of platelets to the microvasculature. Here we demonstrated that the accumulation of platelets in the brain microvasculature can be detected with MRI, using what we believe to be a novel cont...
المؤلفون الرئيسيون: | von Zur Muhlen, C, Sibson, N, Peter, K, Campbell, S, Wilainam, P, Grau, G, Bode, C, Choudhury, R, Anthony, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2008
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مواد مشابهة
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A single-chain antibody directed against activated platelets allows targeted magnetic resonance imaging of human thrombi at clinically relevant field strengths
حسب: von zur Muhlen, C, وآخرون
منشور في: (2005) -
Functionalized magnetic resonance contrast agent selectively binds to glycoprotein IIb/IIIa on activated human platelets under flow conditions and is detectable at clinically relevant field strengths.
حسب: von Zur Muhlen, C, وآخرون
منشور في: (2008) -
Contrast-enhanced ultrasound manifestations of renal masses undetectable on conventional ultrasound
حسب: Lingling Tao, وآخرون
منشور في: (2022-07-01) -
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
حسب: von zur Muhlen, C, وآخرون
منشور في: (2008) -
Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths
حسب: Constantin von zur Mühlen, وآخرون
منشور في: (2008-03-01)