A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI.
Human and murine cerebral malaria are associated with elevated levels of cytokines in the brain and adherence of platelets to the microvasculature. Here we demonstrated that the accumulation of platelets in the brain microvasculature can be detected with MRI, using what we believe to be a novel cont...
Những tác giả chính: | von Zur Muhlen, C, Sibson, N, Peter, K, Campbell, S, Wilainam, P, Grau, G, Bode, C, Choudhury, R, Anthony, D |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2008
|
Những quyển sách tương tự
-
A single-chain antibody directed against activated platelets allows targeted magnetic resonance imaging of human thrombi at clinically relevant field strengths
Bằng: von zur Muhlen, C, et al.
Được phát hành: (2005) -
Functionalized magnetic resonance contrast agent selectively binds to glycoprotein IIb/IIIa on activated human platelets under flow conditions and is detectable at clinically relevant field strengths.
Bằng: von Zur Muhlen, C, et al.
Được phát hành: (2008) -
Contrast-enhanced ultrasound manifestations of renal masses undetectable on conventional ultrasound
Bằng: Lingling Tao, et al.
Được phát hành: (2022-07-01) -
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
Bằng: von zur Muhlen, C, et al.
Được phát hành: (2008) -
Functionalized Magnetic Resonance Contrast Agent Selectively Binds to Glycoprotein IIb/IIIa on Activated Human Platelets under Flow Conditions and Is Detectable at Clinically Relevant Field Strengths
Bằng: Constantin von zur Mühlen, et al.
Được phát hành: (2008-03-01)